Top-down proteomics: Intact proteins are ionized and analyzed directly, allowing for the study of proteoforms and ...

In human cells, lipid droplets (LDs) predominantly contain either cholesteryl esters or triacylglycerols. This article ...

Oncolytic adenovirus was engineered for the forced ectopic delivery of peptide-MHC ligand of T cell receptors (TCRs) to ...

Mitochondrial diseases, arising from mutations in mitochondrial DNA (mtDNA), are a diverse group of disorders that lead to ...

Malaria parasites undergo an extensive metamorphosis after invasion of erythrocytes. This induces an increase in the surface ...

WFS1 and CISD2 regulate IP3R activity through their interaction. In Wolfram syndrome, their dysfunction reduces cytosolic ...

Using genetically predicted metabolic reaction fluxes, the authors identify reactions that can amplify or buffer the effect ...

CD8 T cells lacking Tet1/3 preferentially differentiate into short-lived effector and effector memory cells following acute ...

In Davidi et al , we performed a high-throughput spectrophotometric assay on over 100 rubiscos. The kinetic parameters of the ...

Inflammatory arthritis encompasses a group of autoimmune diseases, including rheumatoid arthritis (RA), psoriatic arthritis ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During somatosensory neurogenesis, neurons are ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Genomics has transformed the diagnostic ...