The 49ers' 2025 schedule will be released on Wednesday, May 14. The NFL will release the 2025 schedule at 5:00 pm Pacific Time. There will be a schedule release special airing on NFL Network.

The 49ers are looking to bounce back in 2025 after a six-win season. How good will they be after a lot of roster turnover this offseason?

Robert Saleh is back in San Francisco as the defensive coordinator, the role he gave up when he left for New York.

The San Francisco 49ers purged a portion of their roster this offseason and loaded up in the 2025 NFL Draft with young ...

The San Francisco 49ers added two former Titans offensive tackles, major contributors to one of the worst two-year periods at ...

They lost Aaron Banks, who's a solid starting left guard, and replaced him with a pupu platter of backups who will compete for the job. They also traded Jordan Mason to the Vikings and replaced him ...

The San Francisco 49ers' decision to release Drake Jackson after a failed physical following a patellar tendon injury could ...

Nick Bosa, the standout defensive end for the San Francisco 49ers, recently signed a significant contract that solidifies his ...

Former Ohio State offensive lineman Nicholas Petit-Frere has signed a one-year free agency deal with the San Francisco 49ers.

Headlining the 49ers’ draft was Mykel Williams, an edge rusher out of Georgia who was the 11th overall pick. In day two, the ...

For four seasons, Robert Saleh was the 49ers’ defensive coordinator under head coach Kyle Shanahan. After middling results from 2017-2018, Saleh coached a dominant unit in 2019 that helped San ...

Check out this article for a list of the San Francisco 49ers 2025-2026 opponents ahead of the NFL schedule release.